Article
High-Throughput GoMiner, an 'industrial-strength' integrative gene ontology tool for interpretation of multiple-microarray experiments, with application to studies of Common Variable Immune Deficiency (CVID).
BMC bioinformatics - 5 Jul 2005
Zeeberg Barry R, Qin Haiying, Narasimhan Sudarshan, Sunshine Margot, Cao Hong, Kane David W, Reimers Mark, Stephens Robert M, Bryant David, Burt Stanley K, Elnekave Eldad, Hari Danielle M, Wynn Thomas A, Cunningham-Rundles Charlotte, Stewart Donn M, Nelson David, Weinstein John N
Abstract excerpt
BACKGROUND: We previously developed GoMiner, an application that organizes lists of 'interesting' genes (for example, under-and overexpressed genes from a microarray experiment) for biological interpretation in the context of the Gene Ontology. The original version of GoMiner was oriented toward visualization and interpretation of the results from a single microarray (or other high-throughput experimental...
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