Article
Global analysis of cellular factors and responses involved in Pseudomonas aeruginosa resistance to arsenite.
Journal of bacteriology - 1 Jul 2005
Parvatiyar Kislay, Alsabbagh Eyad M, Ochsner Urs A, Stegemeyer Michelle A, Smulian Alan G, Hwang Sung Hei, Jackson Colin R, McDermott Timothy R, Hassett Daniel J
Abstract excerpt
The impact of arsenite [As(III)] on several levels of cellular metabolism and gene regulation was examined in Pseudomonas aeruginosa. P. aeruginosa isogenic mutants devoid of antioxidant enzymes or defective in various metabolic pathways, DNA repair systems, metal storage proteins, global regulators, or quorum sensing circuitry were examined for their sensitivity to As(III). Mutants lacking the As(III)...
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