Article
Genetic regulation of IgE responses: Achilles and the tortoise.
The Journal of allergy and clinical immunology - 1 Jul 2005
Vercelli Donata
Abstract excerpt
In the last few decades, basic biology and immunology have thrived, largely thanks to the use of model organisms that allow exploration of complex functions in ideal experimental conditions and genetically defined backgrounds. IgE regulation studies are no exception to this rule. The current challenge is to anchor what we are learning in test tubes and animals to mechanisms of disease in patients with allergy....
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