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Ovarian brain-derived neurotrophic factor (BDNF) promotes the development of oocytes into preimplantation embryos

20 Jun 2005

Abstract excerpt

Optimal development of fertilized eggs into preimplantation embryos is essential for reproduction. Although mammalian oocytes ovulated after luteinizing hormone (LH) stimulation can be fertilized and promoted into early embryos in vitro, little is known about ovarian factors important for the conditioning of eggs for early embryo development. Because LH interacts only with ovarian somatic cells, its potential...

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PMID: 15967989
DOI: 10.1073/pnas.0502442102

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