Article
Association of vitamin D receptor gene polymorphism and Parkinson's disease in Koreans.
Journal of Korean medical science - 1 Jun 2005
Kim Joong-Seok, Kim Yeong-In, Song Christopher, Yoon Injin, Park Jeong-Wook, Choi Young-Bin, Kim Hee-Tae, Lee Kwang-Soo
Abstract excerpt
1alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3), which is the biologically active form of vitamin D, has anti-inflammatory effects and can prevent experimental Parkinson's disease (PD). 1,25(OH)2D3 exerts most of its actions only after it binds to its specific nuclear receptors. Eighty-five Korean patients with PD and 231 unrelated healthy individuals were evaluated to determine if vitamin D receptor gene (VDRG) BsmI...
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