Article
Characterization of ABC transporter ABCB1 expressed in human neural stem/progenitor cells.
FEBS letters - 4 Jul 2005
Islam Mohammed Omedul, Kanemura Yonehiro, Tajria Jesmin, Mori Hideki, Kobayashi Satoshi, Shofuda Tomoko, Miyake Jun, Hara Masayuki, Yamasaki Mami, Okano Hideyuki
Abstract excerpt
We investigated the localization and functional expression of the ABC transporter ABCB1 in human fetal neural stem/progenitor cells (hNSPCs). RT-PCR analysis revealed ABCB1 gene expression in hNSPCs. We found a single band in immunoblotted hNSPCs lysates probed with ABCB1 antibody, and detected ABCB1 at the hNSPCs cell membrane by immunocytochemistry and subcellular fractionation. ABCB1 inhibitors and substrate,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
