Article
Impairing the bioenergetic status and the biogenesis of mitochondria triggers mitophagy in yeast.
Cell death and differentiation - 1 Dec 2005
Priault M, Salin B, Schaeffer J, Vallette F M, di Rago J-P, Martinou J-C
Abstract excerpt
Autophagy, a highly regulated programme found in almost all eukaryotes, is mainly viewed as a catabolic process that degrades nonessential cellular components into molecular building blocks, subsequently available for biosynthesis at a lesser expense than de novo synthesis. Autophagy is largely known to be regulated by nutritional conditions. Here we show that, in yeast cells grown under nonstarving conditions,...
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