Article
Prevalence of hyperhomocysteinaemia, activated protein C resistance and prothrombin gene mutation in inflammatory bowel disease.
European journal of gastroenterology & hepatology - 1 Jul 2005
Mahmood Asif, Needham Jane, Prosser Jeanne, Mainwaring Jason, Trebble Tim, Mahy Gillian, Ramage John
Abstract excerpt
BACKGROUND: Thromboembolic disease is a significant cause of morbidity and mortality in patients with inflammatory bowel disease (IBD). A hypercoagulable state exists in IBD that may involve many components of haemostasis and is closely linked to the disease pathogenesis. It has been proposed that microvascular thrombosis and infarction may trigger the underlying inflammatory process. AIM: To determine the...
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