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Article

Haemophilia A: from mutation analysis to new therapies.

Nature reviews. Genetics - 1 Jun 2005

Graw Jochen, Brackmann Hans-Hermann, Oldenburg Johannes, Schneppenheim Reinhard, Spannagl Michael, Schwaab Rainer

Abstract excerpt

Haemophilia is caused by hundreds of different mutations and manifests itself in clinical conditions of varying severity. Despite being inherited in monogenic form, the clinical features of haemophilia can be influenced by other genetic factors, thereby confounding the boundary between monogenic and multifactorial disease. Unlike sufferers of other genetic diseases, haemophiliacs can be treated successfully by...

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PMID: 15931172
DOI: 10.1038/nrg1617

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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