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Article

[Heterozygous mutation in KCNQ1 cause Jervell and Lange-Nielsen syndrome].

Zhonghua xin xue guan bing za zhi - 1 Jan 2005

Liu Wen-ling, Hu Da-yi, Li Ping, Li Cui-lan, Qin Xu-guang, Li Yun-tian, Li Lei, Li Zhi-ming, Dong Wei, Qi Yu, Wang Qing

Abstract excerpt

OBJECTIVE: Jervell and Lange-Nielsen syndrome (JLNS) is a severe cardioauditory syndrome manifested as QT interval prolongation, abnormal T waves, and relative bradycardia ventricular tachyarrhythmias. In this report, we screened a nonconsanguineous families with JLNS for mutations in KCNQ1. METHODS: Mutation analysis was performed by using purified PCR products to direct sequence analysis on an ABI-3730XL...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15924777

Genes

KCNQ1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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