Article
Polymorphisms in cytochrome P450 17A1 and risk of non-Hodgkin lymphoma.
British journal of haematology - 1 Jun 2005
Skibola Christine F, Lightfoot Tracy, Agana Luz, Smith Alex, Rollinson Sara, Kao Andrew, Adamson Peter, Morgan Gareth J, Smith Martyn T, Roman Eve
Abstract excerpt
Broad cross-talk exists between the endocrine and immune systems. Estrogen receptor expression in lymphocytes suggests that hormonal modulation may influence lymphoma risk. Analysis of genetic polymorphisms that affect oestrogen production, such as cytochrome P450 17A1 (CYP17A1) -34T>C, may provi...
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