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Article

Polymorphisms in cytochrome P450 17A1 and risk of non-Hodgkin lymphoma.

British journal of haematology - 1 Jun 2005

Skibola Christine F, Lightfoot Tracy, Agana Luz, Smith Alex, Rollinson Sara, Kao Andrew, Adamson Peter, Morgan Gareth J, Smith Martyn T, Roman Eve

Abstract excerpt

Broad cross-talk exists between the endocrine and immune systems. Estrogen receptor expression in lymphocytes suggests that hormonal modulation may influence lymphoma risk. Analysis of genetic polymorphisms that affect oestrogen production, such as cytochrome P450 17A1 (CYP17A1) -34T>C, may provide insight into oestrogen's role in lymphomagenesis. CYP17A1-34T>C and CYP17A1 IVS2 105A>C polymorphisms were analyzed...

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Identifiers

PMID: 15916684
DOI: 10.1111/j.1365-2141.2005.05505.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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