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Article

Role of water-soluble amyloid-beta in the pathogenesis of Alzheimer's disease.

International journal of experimental pathology - 1 Jun 2005

Tabaton Massimo, Piccini Alessandra

Abstract excerpt

Water-soluble amyloid-beta (wsAbeta) is present in cerebral cortex of subjects at risk of Alzheimer's disease (AD) as well as in normal elderly subjects as a mixture of three major amyloid-beta (Abeta) species: 1-42, py3-42 and py11-42. The three wsAbeta species are nondetectable in brains of young people, free of immunohistochemically detectable amyloid plaques. In the brains of Down's syndrome and APP-mutant...

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Source

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Identifiers

PMID: 15910548
DOI: 10.1111/j.0959-9673.2005.00428.x
PMCID: PMC2517412

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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