Efflux Pumps and Nosocomial Antibiotic Resistance: A Primer for Hospital Epidemiologists

Abstract excerpt

Bacterial resistance to antimicrobial agents, including multidrug resistance, is an increasing problem in health care in both community and hospital settings. Bacterial adaptability in circumventing antimicrobial action stems from an array of mutational resistance mechanisms and from the acquisition of resistance genes that are present on plasmids that can transfer between bacteria within and among species....

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