Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biomedicine and diseases: the Klippel-Trenaunay syndrome, vascular anomalies and vascular morphogenesis.

Cellular and molecular life sciences : CMLS - 1 Jul 2005

Timur A A, Driscoll D J, Wang Q

Abstract excerpt

Vascular morphogenesis is a vital process for embryonic development, normal physiologic conditions (e.g. wound healing) and pathological processes (e.g. atherosclerosis, cancer). Genetic studies of vascular anomalies have led to identification of critical genes involved in vascular morphogenesis....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenic Proteins
Share to Cardiovascular Abnormalities
Share to NDP gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PDCD10 gene

Share to TIMP3 gene

Share to Genetic Predisposition to Disease

Share to Lymphangiogenesis

Share to Neovascularization, Physiologic

Source

Open in PubMed Open full text

Identifiers

PMID: 15905966
DOI: 10.1007/s00018-005-4523-7
PMCID: PMC1579804

Genes

AGGF1
ENG
FOXC2
NDP
PDCD10
PTEN
RASA1
SOX18
TIMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15905966-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biomedicine and diseases: the Klippel-Trenaunay syndrome, vascular anomalies and vascular morphogenesis.PMID 15905966Read ↗

Update on the Molecular Genetics of Vascular AnomaliesSemantic proximity Read ↗

The Klippel-Trénaunay Syndrome in 2022: Unravelling Its Genetic and Molecular Profile and Its Link to the Limb Overgrowth Syndromes.Semantic proximity Read ↗

Functional characterization of Klippel–Trenaunay syndrome gene AGGF1 identifies a novel angiogenic signaling pathway for specification of vein differentiation and angiogenesis during embryogenesisSemantic proximity Read ↗

Managing Vascular Anomalies in the Era of Genetics and Precision Medicine: An Opportunity or a Challenge?Semantic proximity Read ↗

Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome.Semantic proximity Read ↗

Vascular update: Morphogenesis, tumors, malformations, and molecular dimensionsSemantic proximity Read ↗

Emerging importance of molecular pathogenesis of vascular malformations in clinical practice and classifications.Semantic proximity Read ↗

Vascular development: genetic mechanisms and links to vascular disease.Semantic proximity Read ↗

The Genetic Architecture of Vascular Anomalies: Current Data and Future Therapeutic Perspectives Correlated with Molecular Mechanisms.Semantic proximity Read ↗

Vascular malformations syndromes: an update.Semantic proximity Read ↗

[Pathogenesis and genetics of vascular anomalies].Semantic proximity Read ↗

Haploinsufficiency of Klippel-Trenaunay syndrome gene<i>Aggf1</i>inhibits developmental and pathological angiogenesis by inactivating PI3K and AKT and disrupts vascular integrity by activating VE-cadherinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.