Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association mapping of segregating sites in the early trypsin gene and susceptibility to dengue-2 virus in the mosquito Aedes aegypti.

Insect biochemistry and molecular biology - 1 Jul 2005

Gorrochotegui-Escalante Norma, Lozano-Fuentes Saul, Bennett Kristine E, Molina-Cruz Alvaro, Beaty Barry J, Blackiv William C

Abstract excerpt

Evidence suggests that midgut trypsins in Aedes aegypti condition the mosquito's ability to become infected with the dengue-2 flavivirus (DEN2). The activity of early trypsin protein peaks approximately 3 h after blood feeding and then drops within a few hours. We use association mapping to test the hypothesis that segregating sites in early trypsin condition midgut susceptibility to DEN2 virus. A total of 1642...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aedes
Share to Dengue Virus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Digestive System

Share to Genetic Linkage

Share to Insect Vectors

Share to Quantitative Trait, Heritable

Share to Time Factors

Share to Trypsin

Source

Identifiers

PMID: 15894193
DOI: 10.1016/j.ibmb.2005.02.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association mapping of segregating sites in the early trypsin gene and susceptibility to dengue-2 virus in the mosquito Aedes aegypti.PMID 15894193Read ↗

Characteristics of Trypsin genes and their roles in insecticide resistance based on omics and functional analyses in the malaria vector Anopheles sinensisSemantic proximity Read ↗

The midgut transcriptome of Aedes aegypti fed with saline or protein meals containing chikungunya virus reveals genes potentially involved in viral midgut escapeSemantic proximity Read ↗

Selection of D2S3, an Aedes aegypti (Diptera: Culicidae) strain with high oral susceptibility to Dengue 2 virus and D2MEB, a strain with a midgut barrier to Dengue 2 escape.Semantic proximity Read ↗

Quantitative trait loci that control dengue-2 virus dissemination in the mosquito Aedes aegypti.Semantic proximity Read ↗

Linkage map organization of expressed sequence tags and sequence tagged sites in the mosquito, Aedes aegypti.Semantic proximity Read ↗

Expression profiling and comparative analyses of seven midgut serine proteases from the yellow fever mosquito, Aedes aegyptiSemantic proximity Read ↗

Quantitative trait loci affecting dengue midgut infection barriers in an advanced intercross line of Aedes aegypti.Semantic proximity Read ↗

A targeted approach to the identification of candidate genes determining susceptibility to Plasmodium gallinaceum in Aedes aegypti.Semantic proximity Read ↗

Characterization of a carboxypeptidase A gene from the mosquito, Aedes aegyptiSemantic proximity Read ↗

Nuclear factors bind to a conserved DNA element that modulates transcription of Anopheles gambiae trypsin genes.Semantic proximity Read ↗

Aedes aegypti in Ho Chi Minh City (Viet Nam): susceptibility to dengue 2 virus and genetic differentiation.Semantic proximity Read ↗

Selective inhibitors of digestive enzymes from Aedes aegypti larvae identified by phage display.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.