Constitutive expression of small heat shock protein in an htpG disruptant of the Cyanobacterium Synechococcus sp. PCC 7942.

Abstract excerpt

In cyanobacteria, a disruptant of hspA encoding a small heat shock protein homologue, shows decreased cell growth rates at moderately high temperatures, and loss of both basal and acquired thermo-tolerances, which resemble the phenotype of an htpG disruptant. In vitro studies have shown that both small heat shock protein and Hsp90 can bind and keep non-native proteins in a refolding-competent state under...

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