Article
Establishment of tyrosinase sequence database in normally pigmented Indians and Japanese for rapid determination of novel mutations.
Journal of dermatological science - 1 Sept 2005
Miyamura Yoshinori, Verma Ishwar C, Saxena Renu, Murase Ayumi, Kono Michihiro, Suzuki Tamio, Yasue Satoshi, Shibata Shin-ichi, Sakakibara Akihiro, Tomita Yasushi
Abstract excerpt
BACKGROUND: Many mutations of the tyrosinase gene have been reported in oculocutaneous albinism type I (OCA1) patient. In the future, a greater number of novel mutations will be found as the search for pathological mutations in the tyrosinase genes of OCA patients from various ethnic origins. For rapid determination in future whether an observed mutation is a polymorphism or a novel pathological one, sequence...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.