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Article

The Abantu phenotype in the ABO blood group system is due to a splice-site mutation in a hybrid between a new O1-like allelic lineage and the A2 allele.

Vox sanguinis - 1 May 2005

Hosseini-Maaf B, Smart E, Chester M A, Olsson M L

Abstract excerpt

BACKGROUND AND OBJECTIVES: Many phenotypic variations in the expression of blood group A have been explained by variations in gene structure, but unresolved samples are frequently encountered in the reference laboratory. Among ABO subgroups, A(bantu) has the highest frequency in a specified population. The molecular basis of this phenotype is now described. MATERIALS AND METHODS: Blood from Black donors...

Topics

ABO Blood-Group System
Alleles
Black People
Ethnicity
Exons
Frameshift Mutation
Gene Frequency
Genetic Testing
Humans
Introns
Mutation
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Recombination, Genetic

Source

Identifiers

PMID: 15877647
DOI: 10.1111/j.1423-0410.2005.00626.x

Genes

ABO
AGT

Provenance

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