Article
Comparing age-related macular degeneration phenotype in probands from singleton and multiplex families.
American journal of ophthalmology - 1 May 2005
Postel Eric A, Agarwal Anita, Schmidt Silke, Fan Yu-Ti R, Scott William K, Gilbert John R, Haines Jonathan L, Pericak-Vance Margaret A
Abstract excerpt
PURPOSE: To compare age-related macular degeneration (AMD) phenotype between probands in singleton and multiplex families to determine whether data from these two groups may be combined for consolidated genetic analyses. DESIGN: Retrospective case-control study. METHODS: Individuals 55 years of age or older with AMD were identified. Complete histories and examinations were recorded, 35-mm fundus photographs...
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