Article
Genetic environment and expression of the extended-spectrum beta-lactamase blaPER-1 gene in gram-negative bacteria.
Antimicrobial agents and chemotherapy - 1 May 2005
Poirel Laurent, Cabanne Ludovic, Vahaboglu Haluk, Nordmann Patrice
Abstract excerpt
The genetic location of the gene coding for the expanded-spectrum beta-lactamase PER-1 was analyzed in a series of gram-negative isolates. It was identified as part of a composite transposon bracketed by two novel insertion elements, ISPa12 and ISPa13, belonging to the IS4 family that possess transposases that share 63% amino acid identity and that are chromosomally located in Pseudomonas aeruginosa, Providencia...
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