Article
Quantitative genotyping of single-nucleotide polymorphisms by allele-specific oligonucleotide hybridization on DNA microarrays.
Biotechnology and applied biochemistry - 1 Aug 2005
Rickert Andreas M, Ballvora Agim, Matzner Ulrich, Klemm Manfred, Gebhardt Christiane
Abstract excerpt
Genotyping of SNPs (single-nucleotide polymorphisms) has challenged the development of several novel techniques. Most of these methods have been introduced to discriminate binary SNPs in diploid species. In the present study, the quantitative genotyping of SNPs in natural DNA pools of a polyploid organism via DNA microarrays was analysed. Three randomly selected SNP loci were genotyped in the tetraploid species...
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