Article
Screening candidate genes for mutations in patients with hypogonadotropic hypogonadism using custom genome resequencing microarrays.
American journal of obstetrics and gynecology - 1 Apr 2005
Xu Ning, Podolsky Robert H, Chudgar Pranav, Chorich Lynn P, Liu Chunmei, McDonough Paul G, Warrington Janet A, Layman Lawrence C
Abstract excerpt
OBJECTIVE: The purpose of this study was to determine the consistency of calling single nucleotide polymorphisms (SNPs) by custom genome resequencing microarrays compared with capillary DNA sequencing. STUDY DESIGN: Amplified genomic DNA from 23 patients with hypogonadotropic hypogonadism was hybridized to microarrays containing 30 kilobases of sequence from 6 different candidate genes. Capillary DNA sequencing...
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