Article
The extent of ossification of posterior longitudinal ligament of the spine associated with nucleotide pyrophosphatase gene and leptin receptor gene polymorphisms.
Spine - 15 Apr 2005
Tahara Masamichi, Aiba Atsuomi, Yamazaki Masashi, Ikeda Yoshikazu, Goto Sumio, Moriya Hideshige, Okawa Akihiko
Abstract excerpt
STUDY DESIGN: A case-control study using radiograph findings and the PCR assay with regard to the susceptibility and the severity of ossification of posterior longitudinal ligament of the spine (OPLL). OBJECTIVE: To analyze whether polymorphisms of the nucleotide pyrophosphatase (NPPS) gene and the leptin receptor gene predispose to an increased frequency and severity of OPLL. SUMMARY OF BACKGROUND DATA: The NPPS...
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