Article
Stochasticity or the fatal 'imperfection' of cloning.
Journal of biosciences - 1 Feb 2005
Veitia Reiner A
Abstract excerpt
The concept of clone is analysed with the aim of exploring the limits to which a phenotype can be said to be determined geneticaly. First of all, mutations that result from the replication, topological manipulation or lesion of DNA introduce a source of heritable variation in an otherwise identical genetic background. But more important, stochastic effects in many biological processes may superimpose a phenotypic...
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