Article
Antigenic and phenotypic modifications of Yersinia pestis under calcium and glucose concentrations simulating the mammalian bloodstream environment.
Journal of medical microbiology - 1 May 2005
Feodorova Valentina A, Golova Alina B
Abstract excerpt
To study the possible mechanism of extracellular resistance to phagocytes developed by Yersinia pestis in the early stage of plague infection, the behaviour of two Y. pestis strains, the vaccine EV-76 and fully virulent 231 (LD(50), 10 c.f.u.), was studied in-depth after cultivation in vitro at the host temperature in conditions simulating the bloodstream environment of mammals. For this, two standard basal media...
Topics
- Adaptation, Physiological
- Antigens, Bacterial
- Bacterial Proteins
- Calcium
- Culture Media
- Glucose
- Lipid A
- Phagocytosis
- Phenotype
- Plasminogen Activators
- Yersinia pestis