Article
The relationship of molecular genetic to clinical diagnosis of familial hypercholesterolemia in a Danish population.
Atherosclerosis - 1 May 2005
Damgaard Dorte, Larsen Mogens L, Nissen Peter H, Jensen Jesper M, Jensen Henrik K, Soerensen Vibeke R, Jensen Lillian G, Faergeman Ole
Abstract excerpt
The genes encoding the LDL receptor and apoB were screened for mutations associated with familial hypercholesterolemia (FH) in 408 patients referred to the Lipid Clinic in 1995-2003. The study aimed at testing the ability of three different sets of clinical criteria to predict the results of molecular genetic analysis, and secondly test whether population-based age- and sex-specific percentiles of LDL-cholesterol...
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