Article
A mathematical model for evaluation of maternal cell contamination in cultured cells from spontaneous abortions: significance for cytogenetic analysis of prenatal selection factors.
Fertility and sterility - 1 Apr 2005
Nikitina Tatyana V, Lebedev Igor N, Sukhanova Natalia N, Sazhenova Elena A, Nazarenko Sergey A
Abstract excerpt
OBJECTIVE: To develop a mathematical model for more precise estimation of the incidence of chromosomal abnormalities and the sex ratio among spontaneous abortions masked by maternal cell contamination. DESIGN: Retrospective analysis. SETTING: Academic medical center. PATIENT(S): One hundred twelve samples of spontaneous abortion with a "46,XX" karyotype and 97 parents with aborted embryos. INTERVENTION(S): The...
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