Article
SspA is required for acid resistance in stationary phase by downregulation of H-NS in Escherichia coli.
Molecular microbiology - 1 May 2005
Hansen Anne-Marie, Qiu Yu, Yeh Norman, Blattner Frederick R, Durfee Tim, Jin Ding Jun
Abstract excerpt
The stringent starvation protein A (SspA) is a RNA polymerase-associated protein and is required for transcriptional activation of bacteriophage P1 late promoters. However, the role of SspA in gene expression in Escherichia coli is essentially unknown. In this work, we show that SspA is essential for cell survival during acid-induced stress. Apparently, SspA inhibits stationary-phase accumulation of H-NS, a...
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