Article
Transient gene asymmetry during sporulation and establishment of cell specificity in Bacillus subtilis.
Genes & development - 15 Feb 1999
Frandsen N, Barák I, Karmazyn-Campelli C, Stragier P
Abstract excerpt
Sporulation in Bacillus subtilis is initiated by an asymmetric division generating two cells of different size and fate. During a short interval, the smaller forespore harbors only 30% of the chromosome until the remaining part is translocated across the septum. We demonstrate that moving the gene for sigmaF, the forespore-specific transcription factor, in the trapped region of the chromosome is sufficient to...
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