Article
Two major spondylarthropathy phenotypes are distinguished by pattern analysis in multiplex families.
Arthritis and rheumatism - 15 Apr 2005
Porcher Raphaël, Said-Nahal Roula, D'Agostino Maria-Antonietta, Miceli-Richard Corinne, Dougados Maxime, Breban Maxime
Abstract excerpt
OBJECTIVE: To examine whether spondylarthropathy (SpA) disease manifestations would combine in any ordered pattern among patients from SpA multiplex families. METHODS: SpA patients (n = 540) belonging to 190 multiplex families were thoroughly investigated. Clinical data was collected, systematic pelvic radiographs were taken, and HLA-B27 status was determined. The patterns of SpA manifestations were examined by...
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