Article
Homozygosity mapping of familial glioma in Northern Sweden.
Acta oncologica (Stockholm, Sweden) - 1 Jan 2005
Malmer Beatrice, Haraldsson Susann, Einarsdottir Elisabet, Lindgren Petter, Holmberg Dan
Abstract excerpt
About 5% of glioma cases are familial. Most glioma families are not ascribed to the well-known glioma predisposing syndromes. One segregation analysis has supported an autosomal recessive gene in glioma families, which could be studied by homozygosity mapping. The ancestors of seven glioma families from the northern region of Sweden were traced through genealogical databases. A common ancestor and inbreeding were...
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