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Article

A Thai family with hereditary pancreatitis and increased cancer risk due to a mutation in PRSS1 gene.

World journal of gastroenterology - 21 Mar 2005

Pho-Iam Theeraphong, Thongnoppakhun Wanna, Yenchitsomanus Pa-Thai, Limwongse Chanin

Abstract excerpt

AIM: To investigate mutation of serine protease 1-cationic trypsinogen (CT, PRSS1) gene in members of a Thai family with hereditary pancreatitis and pancreatic cancer. METHODS: Polymerase chain reaction and direct sequencing were performed to analyze the PRSS1 gene in two members of the family affected by pancreatitis. Allele specific amplification (ASA) method was then developed to detect the mutation of the...

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Identifiers

PMID: 15786540
DOI: 10.3748/wjg.v11.i11.1634
PMCID: PMC4305944

Genes

PRSS1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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