Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Polymorphism of methylenetetrahydrofolate reductase and sensitivity of stomach cancer to fluoropyrimidine-based chemotherapy].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Dec 2004

Gao Chang-Ming, Lu Jian-Wei, Toshiro Takezaki, Wu Jian-Zhong, Cao Hai-Xia, Chen Huan-Qiu, Feng Ji-Feng, Kazuo Tajima

Abstract excerpt

OBJECTIVE: To investigate the relationship between polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) C677T or A1298C and the response to fluoropyrimidine (5-FU)-based chemotherapy in advanced stomach cancer (SC). METHODS: 75 cases with advanced SC were analyzed. All patients were treated with 5-FU-based chemotherapy and DNA of peripheral blood leukocytes was obtained before therapy. MTHFR genotypes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Antimetabolites, Antineoplastic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Fluorouracil

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Stomach Neoplasms

Source

Identifiers

PMID: 15769364

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Polymorphism of methylenetetrahydrofolate reductase and sensitivity of stomach cancer to fluoropyrimidine-based chemotherapy].PMID 15769364Read ↗

[Polymorphisms of methylenetetrahydrofolate reductase C677T and the risk of stomach cancer].Semantic proximity Read ↗

[A case-control study on the relationship between methyl-tetra-hydrofolic acid reductase 677 gene polymorphism and the risk of stomach cancer].Semantic proximity Read ↗

[Single nucleotide polymorphisms in methylenetetrahydrofolate reductase gene and susceptibility to cancer of the gastric cardia in Chinese population].Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer susceptibility: an updated meta-analysis.Semantic proximity Read ↗

Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of stomach cancer in a Korean population.Semantic proximity Read ↗

[The relationship between methylenetetrahydrofolate reductase gene polymorphism and microsatellite instability in gastric cancer].Semantic proximity Read ↗

Polymorphisms of 5,10-methylenetetralydrofolate reductase (MTHFR), fruit and vegetable intake, and the risk of stomach cancer.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer susceptibility.Semantic proximity Read ↗

The polymorphism of methylenetetrahydrofolate reductase C677T but not A1298C contributes to gastric cancer.Semantic proximity Read ↗

[Association between genetic variations in methylenetetrahydrofolate reductase and risk of colorectal cancer in a Chinese population].Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer: a meta-analysis.Semantic proximity Read ↗

[Interactions between lifestyle, methylanetetrahydrofolate reductase gene and polymorphisms in thymidylate synthase gene with risk of stomach cancer].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.