Article
Plasma hydroxy-metronidazole/metronidazole ratio in hepatitis C virus-induced liver disease.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Mar 2005
Marchioretto M A M, Ecclissato C, da Silva C M F, Cassiano N M, Calafatti S A, Mendonça S, Ribeiro M L, Bernasconi G C R, Degger M F, Piovesan H, Pedrazzoli J
Abstract excerpt
It has been suggested that the measurement of metronidazole clearance is a sensitive method for evaluating liver function. The aim of this study was to evaluate the usefulness of plasma hydroxy-metronidazole/metronidazole ratios as indicators of dynamic liver function to detect changes resulting from the various forms of chronic hepatitis C virus (HCV) infection. A total of 139 individuals were studied: 14...
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