Article
[Clinicogenetic aspects of carbohydrate metabolism disorders and efficacy of their correction with moxonidine and metformine in patients with arterial hypertension].
Terapevticheskii arkhiv - 1 Jan 2005
Kobalava Zh D, Tolkacheva V V, Ignat'ev I V, Glezer M G, Kuzin A I, Karpov Iu A, Konradi A O, Zheleznykh E A
Abstract excerpt
AIM: To study effects of monotherapy with moxonidine and metformine on metabolic parameters in hypertensive patients with carbohydrate dysbolism (CD) regarding polymorphic markers of genes PPARalpha, PPARgamma and IRS type 1 and 2. MATERIAL AND METHODS: A total of 83 patients (31 male and 52 female patients aged 40-75 years) with untreated arterial hypertension stage I, obesity and CD (by glucose tolerance test)...
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