Article
The ABO blood group genotype and factor VIII levels as independent risk factors for venous thromboembolism.
Thrombosis and haemostasis - 1 Mar 2005
Tirado Isabel, Mateo José, Soria José Manuel, Oliver Arturo, Martínez-Sánchez Elisabeth, Vallvé Cristina, Borrell Monserrat, Urrutia Teresa, Fontcuberta Jordi
Abstract excerpt
Factor VIII (FVIII), von Willebrand factor (vWF) and the ABO blood groups have been associated with thrombosis. The ABO locus has functional effects on vWF and FVIII levels and is genetically correlated with FVIII, vWF and thrombosis. We carried out a case-control study to assess the role of FVIII, vWF and ABO types on thrombotic risk. We analyzed 250 patients with venous thrombosis and 250 unrelated controls....
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