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Factors Characterizing Staphylococcus epidermidis Invasiveness Determined by Comparative Genomics

24 Feb 2005

Abstract excerpt

Virulence mechanisms of the leading nosocomial pathogen Staphylococcus epidermidis are poorly understood. We used microarray-based genome-wide comparison of clinical and commensal S. epidermidis strains to identify putative virulence determinants. Our study revealed high genetic variability of the S. epidermidis genome, new markers for invasiveness of S. epidermidis, and potential targets for drug development...

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PMID: 15731088
DOI: 10.1128/iai.73.3.1856-1860.2005

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