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Article

Roles of Cell Adhesion and Cytoskeleton Activity in <i>Entamoeba histolytica</i> Pathogenesis: a Delicate Balance

24 Feb 2005

Abstract excerpt

The protozoan parasite Entamoeba histolytica colonizes the human large bowel. Invasion of the intestinal epithelium causes amoebic colitis and opens the route for amoebic liver abscesses. The parasite relies on its dynamic actomyosin cytoskeleton and on surface adhesion molecules for dissemination in the human tissues. Here we show that the galactose/N-acetylgalactosamine (Gal/GalNAc) lectin clusters in focal...

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PMID: 15731078
DOI: 10.1128/iai.73.3.1771-1778.2005

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