Article
[Biological characteristics of HIV-1 isolates circulating in China are linked to its env V3 loop sequence variability].
Zhonghua yi xue za zhi - 2 Dec 2004
Hei Fa-xin, Hong Kun-xue, Song Yan-hui, Tang Hai-li, Peng Hong, Xu Jian-qing, Xing Hui, Shao Yi-ming
Abstract excerpt
OBJECTIVE: To investigate the biological characteristics of the HIV-1 isolates circulating in China and to define the association of these properties with env V3 loop sequence variability. METHODS: Primary viruses were isolated from fresh peripheral blood mononuclear cells (PBMCs) using the traditional co-culture method and their capacity of inducing syncytium was tested in MT-2 cells; meanwhile, their coreceptor...
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