Article
Inflammatory cells of immunosuppressive phenotypes in oral lichen planus have a proinflammatory pattern of expression and are associated with clinical parameters.
Clinical oral investigations - 1 Jun 2013
Vered Marilena, Fürth Eran, Shalev Yifat, Dayan Dan
Abstract excerpt
OBJECTIVES: We sought to investigate the expression of cells with immunosuppressive/protumorigenic phenotypes in oral lichen planus (OLP), such as M2-tumor-associated macrophages (TAM2), myeloid-derived suppressive cells (MDSCs), and regulatory T cells (Tregs) in association with clinical parameters. MATERIALS AND METHODS: Cases of hyperkeratotic (HK)-OLP (n = 23) and erosive (E)-OLP (n = 26) were...
Topics
- Adult
- Aged
- Antigens, CD
- Antigens, Differentiation, Myelomonocytic
- B7-1 Antigen
- Female
- Humans
- Immune Tolerance
- Inflammation
- Lichen Planus, Oral
- Macrophages
- Male
- Middle Aged
- NF-kappa B