Article
[Surfactant protein A gene polymorphisms in chronic obstructive pulmonary disease].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2005
Xie Jun-gang, Xu Yong-jian, Zhang Zhen-xiang, Ni Wang, Chen Shi-xin
Abstract excerpt
OBJECTIVE: To investigate whether polymorphism in gene for surfactant protein A(SPA) has any bearing on individual susceptibility to the development of chronic obstructive pulmonary disease(COPD). METHODS: The genotypes of 88 patients with COPD and 87 healthy smoking subjects as controls were tested with polymerase chain reaction followed by restriction fragment length polymorphism analysis for SPA gene. RESULTS:...
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