Article
Heart rate influences on repolarization duration and morphology in symptomatic versus asymptomatic KCNQ1 mutation carriers.
The American journal of cardiology - 1 Feb 2005
Extramiana Fabrice, Denjoy Isabelle, Badilini Fabio, Chabani Iheb, Neyroud Nathalie, Berthet Myriam, Fressard Véronique, Guicheney Pascale, Beaufils Philippe, Leenhardt Antoine, Coumel Philippe, Maison-Blanche Pierre
Abstract excerpt
QT and Tp/Te intervals were longer in patients with LQT1 (n = 67) than in nonaffected subjects (n = 52) but did not differentiate symptomatic (n = 21) from asymptomatic patients (n = 46). At fast heart rate, the time to accumulate the last part of total T-wave area (the t50-97 interval) was longer in symptomatic carriers compared with asymptomatic patients (119 +/- 19 vs 106 +/- 15 ms, p <0.01). The latter group...
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