Article
Molecular mechanisms of high level tetracycline-resistance in group A streptococcal isolates, T serotypes 4 and 11.
International journal of antimicrobial agents - 1 Feb 2005
Matsumoto Masakado, Sakae Kenji, Ohta Michio, Endo Miyoko, Okuno Rumi, Murayama Shoko, Hirasawa Kyoko, Suzuki Rieko, Isobe Junko, Tanaka Daisuke, Katsukawa Chihiro, Tamaru Aki, Tomita Masaaki, Ogata Kikuyo, Yasuoka Tomihisa, Ikebe Tadayoshi, Watanabe Haruo
Abstract excerpt
The molecular mechanism of high level tetracycline resistance in T serotypes 4 and 11 group A streptococcal (GAS) isolates was examined in 61 tetracycline-resistant isolates in Japan. PCR and sequencing analyses revealed that the T serotype/emm genotype, T4/4 isolates carried tet(O) genes, which...
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