Genetic diversity of the tet(M) gene in tetracycline-resistant clonal lineages of Streptococcus pneumoniae.

doi:10.1128/AAC.44.11.2979-2984.2000

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Article

Genetic diversity of the tet(M) gene in tetracycline-resistant clonal lineages of Streptococcus pneumoniae.

Antimicrobial agents and chemotherapy - 1 Nov 2000

Doherty N, Trzcinski K, Pickerill P, Zawadzki P, Dowson C G

Abstract excerpt

The aim of the present study was to examine the stability and evolution of tet(M)-mediated resistance to tetracyclines among members of different clonal lineages of Streptococcus pneumoniae. Thirty-two tetracycline-resistant isolates representing three national (Spanish serotype 14, Spanish serotype 15, and Polish serotype 23F) and one international (Spanish serotype 23F) multidrug-resistant epidemic clones were...

Topics

Bacterial Proteins
Cell Lineage
DNA Transposable Elements
Genetic Variation
Integrases
Restriction Mapping
Streptococcus pneumoniae
Tetracycline Resistance

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Identifiers

PMID: 11036009
DOI: 10.1128/AAC.44.11.2979-2984.2000
PMCID: PMC101589

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