Validating viral quasispecies with digital organisms: a re-examination of the critical mutation rate.

Abstract excerpt

BACKGROUND: In this report we re-examine some recent experiments with digital organisms to test some predictions of quasispecies theory. These experiments revealed that under high mutation rates populations of less fit organisms previously adapted to such high mutation rates were able to outcompete organisms with higher average fitness but adapted to low mutation rates. RESULTS: We have verified that these...

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