Article
Timing of the retinoid-signalling pathway determines the expression of neuronal markers in neural progenitor cells.
Developmental biology - 1 Feb 2005
Goncalves Maria Beatriz C V, Boyle Julia, Webber Daniel J, Hall Sara, Minger Stephen L, Corcoran Jonathan P T
Abstract excerpt
By culturing neural progenitor cells in the presence of retinoid receptor agonists, we have defined the components of the retinoid-signalling pathway that are important for the birth and maintenance of neuronal cells. We provide evidence that depending on the order and combination of retinoid receptors activated, different neuronal cells are obtained. Astrocytes and oligodendrocytes are predominantly formed in...
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