Multiple sclerosis. Observations and reflections--a personal memoir.

Abstract excerpt

The pathogenesis of MS has become better understood as a result of recent advances in several areas, particularly in epidemiology and neuro-imaging. A number of epidemiologically based conclusions need to be revised, most importantly the putative direct relationship between prevalence and latitude, and the concept that epidemics of MS have occurred in some parts of the world. It is now clear that genetic factors...

Topics

• Blood-Brain Barrier
• Genetic Predisposition to Disease
• HLA Antigens
• Humans
• Multiple Sclerosis
• Prevalence