Article
[Deletions in the dystrophin gene and its phenotype expression].
Srpski arhiv za celokupno lekarstvo - 1 Jan 2000
Lalić T, Guć-Sćekić M, Djurisić M, Radivojević D, Zamurović D, Todorović S
Abstract excerpt
About 60% of both Duchenne's muscular dystrophy (DMD) and Becker's muscular dystrophy (BMD) is due to deletions of dystrophin gene. For cases with deletion mutations the "reading frame" hypothesis predicts that deletions which result in disruption of the translation reading frame prevent production of stable protein and are associated with DMD. In contrast, intragenic deletions that involve exons encoding an...
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