Article
[Molecular genetics of Duchenne/Becker muscular dystrophy].
Nihon rinsho. Japanese journal of clinical medicine - 1 Sept 1993
Saito K, Ikeya K, Kondo E, Yamauchi A, Komine S, Fukuyama Y
Abstract excerpt
The X-linked gene responsible for Duchenne muscular dystrophy (DMD)/Becker muscular dystrophy (BMD) encodes dystrophin, a high-molecular-weight cytoskeletal protein. The identification of the dystrophin gene through positional cloning, and the subsequent description of its protein product have op...
Topics
- Animals
- Cloning, Molecular
- Dystrophin
- Humans
- Mice
- Molecular Structure
- Molecular Weight
- Muscles
- Muscular Dystrophies
- Mutation
- Phenotype