Molecular characterization of a Drosophila melanogaster variant strain defective in the Sgs-4 gene dosage compensation.

doi:10.1016/0167-4781(92)90444-5

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Article

Molecular characterization of a Drosophila melanogaster variant strain defective in the Sgs-4 gene dosage compensation.

Biochimica et biophysica acta - 6 Apr 1992

Furia M, Digilio F A, Artiaco D, Favia G, Polito L C

Abstract excerpt

The X-linked Sgs-4 gene of Drosophila melanogaster encodes a salivary glue protein. Here we report the molecular characterization of a non-dosage compensated variant strain, named Karsnas, in which males accumulate only about half of the Sgs-4 polypeptide amount as do females. The results obtaine...

Topics

Animals
Base Sequence
Dosage Compensation, Genetic
Drosophila melanogaster
Female
Glue Proteins, Drosophila
Male
Molecular Sequence Data
Mutation
Regulatory Sequences, Nucleic Acid

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